Dear Editor:We greatly appreciate the insights from your multicenter trial on thymosin α1 for sepsis and seek clarification on two key aspects to deepen our understanding of the findings. First, regarding the subgroup analysis showing potential differential effects by age (hazard ratio 1.67 for <60 years vs. 0.81 for ≥60 years, P for interaction=0.01) and […]
Dear Editor The CONSORT (2025) statement [1] writes about blinding as follows: “Unblinded outcome assessors may differentially assess subjective outcomes, and unblinded data analysts may introduce bias through the choice of analytical strategies, such as the selection of favourable time points or outcomes and by decisions to remove patients from the analyses. These biases have […]
At the 15mg dose, participants showed a sustained average weight loss of 22.9% during the three-year treatment. Credit: SB Arts Media / Shutterstock. Eli Lilly has reported comprehensive outcomes from the SURMOUNT-1 study of tirzepatide (Zepbound and Mounjaro) for treating pre-diabetic and obese individuals. Spanning 176 weeks of treatment, the Phase III trial evaluated the efficacy […]
Gubra’s once-weekly obesity candidate was tied | Gubra’s once-weekly obesity candidate was tied to 3% weight loss during a six-week phase 1 trial, with a single injection also linked to weight reduction.
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Retailers Can Elevate Their Store’s Snack Selection with Crispy Green’s Best-selling Freeze-dried Fruit Flavors FAIRFIELD, N.J. — Crispy Green, the maker of Crispy Fruit, the top-selling freeze-dried fruit snack in the U.S., is helping retailers prepare for the January wellness rush by introducing its new seasonal Crispy Fruit Trial Pack. The Trial Pack, available now in limited […]
In good news for those averse to injections, GLP-1 agonist medication is a step closer to being offered in oral pill form, with AstraZeneca revealing “encouraging data” out of its Phase I study of its obesity and diabetes drug AZD5004. In a presentation at the ObesityWeek conference in San Antonio this week, the UK pharmaceutical […]
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