Re: Palliative care is an overlooked global health priority
Studies & Findings

Are Subgroup Analysis and Sample Size Considerations Adequate in the TESTS Trial?

Dear Editor:We greatly appreciate the insights from your multicenter trial on thymosin α1 for sepsis and seek clarification on two key aspects to deepen our understanding of the findings. First, regarding the subgroup analysis showing potential differential effects by age (hazard ratio 1.67 for <60 years vs. 0.81 for ≥60 years, P for interaction=0.01) and […]

Ulcerative Colitis Diagnosis: Colonoscopy, Blood and Stool Tests, and More
Diabetes Care

Colonoscopy, Blood and Stool Tests, and More

The only way to diagnose UC with certainty is by testing a small sample of tissue from your intestines during a colonoscopy. This is known as a biopsy. [3] But other tests are used to confirm a UC diagnosis, check its severity, see how much of the large intestine is affected, identify complications, and assess […]

FDA doesn’t appeal court ruling invalidating lab-developed tests rule, effectively eliminating it
Health Systems

FDA doesn’t appeal court ruling invalidating lab-developed tests rule, effectively eliminating it

A 60-day appeal window has passed for the Food and Drug Administration to appeal a federal court ruling that invalidated its final rule to regulate laboratory-developed tests as medical devices, effectively eliminating it. The rule, issued last year, would have phased out its general enforcement discretion approach for most lab-developed tests over four years. The […]

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