At the 15mg dose, participants showed a sustained average weight loss of 22.9% during the three-year treatment. Credit: SB Arts Media / Shutterstock. Eli Lilly has reported comprehensive outcomes from the SURMOUNT-1 study of tirzepatide (Zepbound and Mounjaro) for treating pre-diabetic and obese individuals. Spanning 176 weeks of treatment, the Phase III trial evaluated the efficacy […]
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Magnetic fields to control neurons remotely? A cutting-edge technology, magnetogenetics, now allows the inhibition or activation of brain circuits in mice remotely, without implants. Scientists at Rockefeller University have modified genes to make certain neurons sensitive to magnetic fields. By controlling the neural circuits linked to Parkinson’s disease, they observed a significant improvement in movement. […]
Long-acting pharmacotherapies targeting incretin hormones like glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) have revolutionized treatments for obesity and type 2 diabetes (T2D). These therapies have provided millions with sustained weight loss and better glucose management. For many, GLP-1 receptor agonists offer a lifeline, achieving weight loss comparable to bariatric surgery. Yet, the success […]
A new Lancet study has found that almost three-quarters of adults in the U.S. are overweight or obese, calling it a “crisis point” for the country. In 1990, about half of adults fit that definition. And now, people are becoming obese at younger ages, according to the study. Dr. Steven Gortmaker, director of the Harvard […]
Everyone deserves access to effective obesity treatment, and we have the power to remove barriers to that treatment. Since the 1980s, adult obesity rates have more than doubled to over 42% of Americans. Excess weight causes over 500,000 deaths in the U.S. each year. Obesity and related chronic illnesses led to more than $480 billion in direct health care costs and […]
Nogueiras, R., Nauck, M. A. & Tschöp, M. H. Nature Metab. 5, 933–944 (2023). Article PubMed Google Scholar Christoffersen, B. Ø. et al. Obesity 30, 841–857 (2022). Article PubMed Google Scholar Sass, F. et al. Nature (2024). Article Google Scholar Wilding, J. P. H. et al. N. Engl. J. Med. 384, 989–1002 (2021). Article PubMed […]
Welcome back to this special World Diabetes Day edition Diabetes Dialogue: Technology, Therapeutics, & Real-World Perspectives! Key Timestamps and Highlights 00:00 Introduction and discussion of GLP-1 agonist shortages 0:03:34 Compounded medications and FDA regulations 0:07:30 Discussion of tirzepatide clinical efficacy 0:10:27 Long-term benefits and future prospects In this episode, hosts Diana Isaacs, PharmD, an endocrine clinical […]
Gubra’s once-weekly obesity candidate was tied | Gubra’s once-weekly obesity candidate was tied to 3% weight loss during a six-week phase 1 trial, with a single injection also linked to weight reduction.
Hypothalamic Obesity Treatment Market || 2024-2031 The Hypothalamic Obesity Treatment Market study by DataM Intelligence offer an in-depth analysis of the market, presenting insightful observations, statistics, historical data, and industry-validated market insights. The report delves into the competitive positioning of key companies, examining factors such as product offerings, pricing strategies, financial health, product portfolios, growth […]
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